Search results for "protein–membrane interactions"

showing 1 items of 1 documents

Transportan 10 Induces Perturbation and Pores Formation in Giant Plasma Membrane Vesicles Derived from Cancer Liver Cells

2023

Continuous progress has been made in the development of new molecules for therapeutic purposes. This is driven by the need to address several challenges such as molecular instability and biocompatibility, difficulties in crossing the plasma membrane, and the development of host resistance. In this context, cell-penetrating peptides (CPPs) constitute a promising tool for the development of new therapies due to their intrinsic ability to deliver therapeutic molecules to cells and tissues. These short peptides have gained increasing attention for applications in drug delivery as well as for their antimicrobial and anticancer activity but the general rules regulating the events involved in cell…

cell-penetrating peptidesdi-4-ANEPPDHQprotein–membrane interactionsgiant plasma membrane vesiclesprotein–membrane interactions; cell-penetrating peptides; Transportan 10; giant plasma membrane vesicles; phasor approach; Nile Red; di-4-ANEPPDHQ; membrane hydrationTransportan 10Nile RedMolecular BiologyBiochemistryphasor approachSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)membrane hydration
researchProduct